The mitochondrial outer membrane (MOM) mediates multiple interactions between the mitochondrial metabolic and genetic systems and the rest of the eukaryotic cell. Biogenesis of this membrane involves integration of newly synthesized proteins into the lipid bilayer. Among these precursor proteins are those that span the membrane once, twice or with multiple segments. Our aim is to fully define the biological processes and molecular mechanisms that underlie the biogenesis of MOM proteins. Employing in vitro, in organello and in vivo experiments we could characterize unique import pathways for the various families of MOM proteins. Remarkably, the biogenesis of β-barrel proteins is conserved from Gram–negative bacteria to mitochondria and this conservation allows the organelle to recognized and process bacterial substrates.

日時	2016年10月20日（木）16:00～17:00（15:45開場）
場所	京都産業大学 15号館1階15102セミナー室
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共催	日本学術振興会外国人研究者招へい事業［外国人招へい研究者（短期）］
世話人	京都産業大学　総合生命科学部　教授　遠藤 斗志也
備考	事前申込不要・入場無料